{"id":328,"date":"2025-07-01T23:06:18","date_gmt":"2025-07-01T23:06:18","guid":{"rendered":"https:\/\/staging-3.com\/university\/?p=328"},"modified":"2025-08-21T23:38:51","modified_gmt":"2025-08-21T23:38:51","slug":"neural-development-stem-cell-biology","status":"publish","type":"post","link":"https:\/\/staging-3.com\/university\/neural-development-stem-cell-biology\/","title":{"rendered":"Neural Development &amp; Stem Cell Biology"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"328\" class=\"elementor elementor-328\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-05af96c elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"05af96c\" data-element_type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-563d1ed\" data-id=\"563d1ed\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d611a50 elementor-widget elementor-widget-heading\" data-id=\"d611a50\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">know us better<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-beacc34 elementor-hidden-tablet elementor-hidden-phone\" data-id=\"beacc34\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-d21a474 elementor-widget elementor-widget-jkit_button\" data-id=\"d21a474\" data-element_type=\"widget\" data-widget_type=\"jkit_button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div  class=\"jeg-elementor-kit jkit-button  icon-position-before jeg_module___69f2f33542ded\" ><a href=\"https:\/\/staging-3.com\/university\/\" class=\"jkit-button-wrapper\">Home<\/a><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t<div class=\"elementor-element elementor-element-7e256ff e-flex e-con-boxed e-con e-parent\" data-id=\"7e256ff\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3845ba7 elementor-widget elementor-widget-heading\" data-id=\"3845ba7\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Neural Development &amp; Stem Cell Biology\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ddce2e7 elementor-widget elementor-widget-text-editor\" data-id=\"ddce2e7\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div id=\"w-node-_2f8d3e0b-498b-c911-f27e-38538f6a6f64-c4dfe29c\" class=\"rl-text-rich-text w-richtext\" data-w-id=\"2f8d3e0b-498b-c911-f27e-38538f6a6f64\" data-wf-id=\"[&quot;2f8d3e0b-498b-c911-f27e-38538f6a6f64&quot;]\"><p data-w-id=\"096ab3c3-6524-ba7b-05c9-cb284df850a3\" data-wf-id=\"[&quot;096ab3c3-6524-ba7b-05c9-cb284df850a3&quot;]\">We are interested in the lineage steps in the development of the mammalian brain from totipotent embryonic stem (blastocyst) cells to neural stem cells to more restricted neural progenitor cells that make neurons and glia. Of particular interest are the earliest steps in the production of self-renewing neural stem cells from mouse embryonic stem cells, in terms of discovering novel and testing candidate neural determination genes. Neural stem cells also are present in adult and even elderly mammalian brains, and these stem cells are being localized in adult brains and being characterized in terms of their proliferative kinetics and growth factor requirements in vivo and in vitro. Finally adult neural stem cells can produce new neurons and glia in adult mammalian brains in vivo and we are testing the ability of these new cells to re-establish function in animal models of human neurological disorders.<\/p><p data-w-id=\"d7e6e423-9d5c-63e5-93d4-b90db00e6d86\" data-wf-id=\"[&quot;d7e6e423-9d5c-63e5-93d4-b90db00e6d86&quot;]\">Development and Stem\u00a0Cell Biology is divided into four main areas of interest:<\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0a93df9 e-flex e-con-boxed e-con e-parent\" data-id=\"0a93df9\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-7a5540f e-con-full e-flex e-con e-child\" data-id=\"7a5540f\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c26a7e0 elementor-widget elementor-widget-image\" data-id=\"c26a7e0\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"412\" height=\"189\" src=\"https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/666c743cb9cc5576d3449b36_bct-photo-2-1.jpg\" class=\"attachment-full size-full wp-image-334\" alt=\"\" srcset=\"https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/666c743cb9cc5576d3449b36_bct-photo-2-1.jpg 412w, https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/666c743cb9cc5576d3449b36_bct-photo-2-1-300x138.jpg 300w\" sizes=\"(max-width: 412px) 100vw, 412px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a46a832 elementor-widget elementor-widget-heading\" data-id=\"a46a832\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Retinal Stem Cells and Eye\n<BR> Development<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b4b8f71 elementor-widget elementor-widget-jkit_button\" data-id=\"b4b8f71\" data-element_type=\"widget\" data-widget_type=\"jkit_button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div  class=\"jeg-elementor-kit jkit-button  icon-position-before jeg_module__1_69f2f33543a0c\" ><a href=\"https:\/\/staging-3.com\/university\/retinal-stem-cells-and-eye-development\/\" class=\"jkit-button-wrapper\">Read More <\/a><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-989dd7e e-con-full e-flex e-con e-child\" data-id=\"989dd7e\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0496bf1 elementor-widget elementor-widget-image\" data-id=\"0496bf1\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"2000\" height=\"1500\" src=\"https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/666c749cde5a203d9fb06b94_NEURAL-PRECURSOR-CELLS-Samantha-Yammine.jpg\" class=\"attachment-full size-full wp-image-330\" alt=\"\" srcset=\"https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/666c749cde5a203d9fb06b94_NEURAL-PRECURSOR-CELLS-Samantha-Yammine.jpg 2000w, https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/666c749cde5a203d9fb06b94_NEURAL-PRECURSOR-CELLS-Samantha-Yammine-300x225.jpg 300w, https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/666c749cde5a203d9fb06b94_NEURAL-PRECURSOR-CELLS-Samantha-Yammine-1024x768.jpg 1024w, https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/666c749cde5a203d9fb06b94_NEURAL-PRECURSOR-CELLS-Samantha-Yammine-768x576.jpg 768w, https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/666c749cde5a203d9fb06b94_NEURAL-PRECURSOR-CELLS-Samantha-Yammine-1536x1152.jpg 1536w\" sizes=\"(max-width: 2000px) 100vw, 2000px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d597f69 elementor-widget elementor-widget-heading\" data-id=\"d597f69\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Cell Lineage and Neural <BR>Development\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-acb9d0f elementor-widget elementor-widget-jkit_button\" data-id=\"acb9d0f\" data-element_type=\"widget\" data-widget_type=\"jkit_button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div  class=\"jeg-elementor-kit jkit-button  icon-position-before jeg_module__2_69f2f33543eab\" ><a href=\"https:\/\/staging-3.com\/university\/cell-lineage-and-neural-development\/\" class=\"jkit-button-wrapper\">Read More <\/a><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0cbf899 e-flex e-con-boxed e-con e-parent\" data-id=\"0cbf899\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-7ef81cb e-con-full e-flex e-con e-child\" data-id=\"7ef81cb\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f7f7d90 elementor-widget elementor-widget-image\" data-id=\"f7f7d90\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"2400\" height=\"1901\" src=\"https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/6679ac1736a0aab16aab3078_CELL-PROGENCY-FROM-PANCREAS-DERIVED-PRECURSOR-CELL-Simon-Smukler.jpg\" class=\"attachment-full size-full wp-image-341\" alt=\"\" srcset=\"https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/6679ac1736a0aab16aab3078_CELL-PROGENCY-FROM-PANCREAS-DERIVED-PRECURSOR-CELL-Simon-Smukler.jpg 2400w, https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/6679ac1736a0aab16aab3078_CELL-PROGENCY-FROM-PANCREAS-DERIVED-PRECURSOR-CELL-Simon-Smukler-300x238.jpg 300w, https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/6679ac1736a0aab16aab3078_CELL-PROGENCY-FROM-PANCREAS-DERIVED-PRECURSOR-CELL-Simon-Smukler-1024x811.jpg 1024w, https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/6679ac1736a0aab16aab3078_CELL-PROGENCY-FROM-PANCREAS-DERIVED-PRECURSOR-CELL-Simon-Smukler-768x608.jpg 768w, https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/6679ac1736a0aab16aab3078_CELL-PROGENCY-FROM-PANCREAS-DERIVED-PRECURSOR-CELL-Simon-Smukler-1536x1217.jpg 1536w, https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/6679ac1736a0aab16aab3078_CELL-PROGENCY-FROM-PANCREAS-DERIVED-PRECURSOR-CELL-Simon-Smukler-2048x1622.jpg 2048w\" sizes=\"(max-width: 2400px) 100vw, 2400px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-48fd9d8 elementor-widget elementor-widget-heading\" data-id=\"48fd9d8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Pancreatic Stem Cells\n\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d39086d elementor-widget elementor-widget-jkit_button\" data-id=\"d39086d\" data-element_type=\"widget\" data-widget_type=\"jkit_button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div  class=\"jeg-elementor-kit jkit-button  icon-position-before jeg_module__3_69f2f3354432d\" ><a href=\"https:\/\/staging-3.com\/university\/pancreatic-stem-cells\/\" class=\"jkit-button-wrapper\">Read More <\/a><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7e25f83 elementor-widget elementor-widget-text-editor\" data-id=\"7e25f83\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Photo Credit: Brenda Coles-Takabe, Samantha Yammine, and Simon Smukler<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2a44b16 e-con-full e-flex e-con e-child\" data-id=\"2a44b16\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0671b1f elementor-widget elementor-widget-image\" data-id=\"0671b1f\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"945\" height=\"945\" src=\"https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/66a181f6d20723cdcf189eac_KarpowiczImage.jpg\" class=\"attachment-full size-full wp-image-342\" alt=\"\" srcset=\"https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/66a181f6d20723cdcf189eac_KarpowiczImage.jpg 945w, https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/66a181f6d20723cdcf189eac_KarpowiczImage-300x300.jpg 300w, https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/66a181f6d20723cdcf189eac_KarpowiczImage-150x150.jpg 150w, https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/66a181f6d20723cdcf189eac_KarpowiczImage-768x768.jpg 768w, https:\/\/staging-3.com\/university\/wp-content\/uploads\/2025\/07\/66a181f6d20723cdcf189eac_KarpowiczImage-600x600.jpg 600w\" sizes=\"(max-width: 945px) 100vw, 945px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3e0e9c2 elementor-widget elementor-widget-heading\" data-id=\"3e0e9c2\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Asymmetrical Division\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-682d28a elementor-widget elementor-widget-jkit_button\" data-id=\"682d28a\" data-element_type=\"widget\" data-widget_type=\"jkit_button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div  class=\"jeg-elementor-kit jkit-button  icon-position-before jeg_module__4_69f2f33544a7e\" ><a href=\"https:\/\/staging-3.com\/university\/asymmetrical-division\/\" class=\"jkit-button-wrapper\">Read More <\/a><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>know us better Home Neural Development &amp; Stem Cell Biology We are interested in the lineage steps in the development of the mammalian brain from totipotent embryonic stem (blastocyst) cells to neural stem cells to more restricted neural progenitor cells that make neurons and glia. Of particular interest are the earliest steps in the production [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":193,"comment_status":"open","ping_status":"open","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-328","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","entry","has-media"],"_links":{"self":[{"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/posts\/328","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/comments?post=328"}],"version-history":[{"count":31,"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/posts\/328\/revisions"}],"predecessor-version":[{"id":981,"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/posts\/328\/revisions\/981"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/media\/193"}],"wp:attachment":[{"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/media?parent=328"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/categories?post=328"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/tags?post=328"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}