{"id":445,"date":"2025-07-02T18:19:34","date_gmt":"2025-07-02T18:19:34","guid":{"rendered":"https:\/\/staging-3.com\/university\/?page_id=445"},"modified":"2025-08-21T23:55:29","modified_gmt":"2025-08-21T23:55:29","slug":"publications","status":"publish","type":"page","link":"https:\/\/staging-3.com\/university\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\t\t
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know us better<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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recent publications<\/a><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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2025 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Jacques K, Coles BLK, van der Kooy D. Pancreatic stem cells originate during the pancreatic progenitor developmental stage. Front Cell Dev Biol. 2025 Feb 18;13:1521411. doi: 10.3389\/fcell.2025.1521411. PMID: 40040790; PMCID: PMC11876382.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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2024 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Maal-Bared, G., \u00a0Yee, M., \u00a0Harding, E. K., \u00a0Ghebreselassie, M., \u00a0Bergamini, M., \u00a0Choy, R., \u00a0Kim, E., \u00a0Di Vito, S., Patel, M., \u00a0Amirzadeh, M., \u00a0Grieder, T. E., \u00a0Coles, B. L., \u00a0Nagy, J. I., \u00a0Bonin, R. P., \u00a0Steenland, H. W., & \u00a0D.van der Kooy (2024). \u00a0Connexin-36-positive gap junctions in ventral tegmental area GABA neurons sustain opiate dependence. European Journal of Neuroscience, \u00a059(12), \u00a03422\u20133444.\u00a0https:\/\/doi.org\/10.1111\/ejn.16366
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\u200d<\/em><\/a>Mokady D, Charish J, Barretto-Burns P, Gris\u00e9 KN, Coles BLK, Raab S, Ortin-Martinez A, Mu\u0308ller A,Fasching B, Jain P, Drukker M, van der Kooy D, Steger M. (2024). Small-Molecule-Directed Endogenous Regeneration of Visual Function in a Mammalian Retinal Degeneration Model. International Journal of Molecular Sciences. 25(3): 1521-1539.http:\/\/dx.doi.org\/10.3390\/ijms25031521<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Vargas-Perez H, Minauro-Sanmiguel F, Ting-A-Kee R, Grieder TE, M\u00e9ndez-D\u00edaz M, Prosp\u00e9ro-Garc\u00eda O, van der Kooy D. Rewarding Effects of the Hallucinogen 4-AcO-DMT Administration and Withdrawal in Rats: A Challenge to the Opponent-Process Theory. Neurosci Lett. 2024 Jan 18;820:137597.\u00a0doi: 10.1016\/j.neulet.2023.137597<\/a><\/p><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/section>

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2023 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Vargas-Perez H, Grieder T, van der Kooy D (van der Kooy’s h-index 104). (2023). Neural plasticity in theventral tegmental area, aversive motivation during drug withdrawal and hallucinogenic therapy. Journal of Psychoactive Drugs. 55(1): 62-72.https:\/\/doi.org\/10.1080\/02791072.2022.2033889<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\nYammine S, Burns I, Gosio J, Peluso A, Merritt D, Innes B, Coles B, Yan WR, Bader GD, Morshead C, van der Kooy D. (2023). Fate specification of GFAP-negative primitive neural stem cells and their progeny at clonal resolution. Stem Cells and Development.https:\/\/doi.org\/10.1089\/scd.2023.0038<\/a>\n\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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2022 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Merritt DM, MacKay-Clackett I, Almeida SMT, Tran C, Ansar S, van der Kooy D. (2022). Arrestin-mediated Desensitization Enables Olfactory Discrimination in C. elegans. PNAS. 119(31): e2116957119.http:\/\/dx.doi.org\/doi:10.1073\/pnas.2116957119<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\tGrieder TE, Yee M, Vargas-Perez H, Maal-Bared G, George S, Ting-A-Kee R, George O, van der Kooy D. (2022). Administration of BDNF in the ventral tegmental area produces a switch from a nicotine-nondependent D1R-mediated motivational state to a nicotine-dependent-like D2R-mediated motivational state. European Journal of Neuroscience. 55(3): 714-724.https:\/\/doi.org\/10.1111\/ejn.15579\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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2021 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Gris\u00e9 KN, Coles BLK, Bautista NX, van der Kooy D. (2021). Activation of adult mammalian retinal stemcells in vivo via antagonism of BMP and sFRP2. Stem Cell Research & Therapy. 12(1): 560.\u00a0https:\/\/doi.org\/10.1186\/s13287-021-02630-0<\/a>

Adams K, Neemat M, Green-Holland M, Vonderwalde I, Umebayashi D, Sachewsky N, Coles BLK, vander Kooy D, Morshead CM. (2021). Constraint-induced movement therapy promotes motor recovery afterneonatal stroke in the absence of neural precursor activation. European Journal of Neuroscience. 53(4):1334:1349.http:\/\/dx.doi.org\/doi.org\/10.1111\/ejn.14993<\/a>

Baker AEG, Cui H, Ballios BG, Ing S, Yan P, Wolfer J, Wright T, Dang M, Gan NY, Cooke MJ, Ort\u00edn-Mart\u00ednez A, Wallace VA, van der Kooy D, Devenyi R, Shoichet MS. (2021). Stable oxime-crosslinked hyaluronan-based hydrogel as a biomimetic vitreous substitute. Biomaterials. 271: 120750.https:\/\/doi.org\/10.1016\/j.biomaterials.2021.120750<\/a>

Baakdhah TW, Coles BL, van der Kooy S. (2021). A defined subset of clonal retinal stem cell spheres isbiased to RPE differentiation. iScience. 24(6): 102574.https:\/\/doi.org\/10.1016\/j.isci.2021.102574<\/a>

Coles BLK, Labib M, Poudineh M, Innes BT, Belair-Hickey J, Gomis S, Wang Z, Bader GD, SargentEH, Kelley OS, van der Kooy D. (2021). A microfluidic platform enables comprehensive gene expressionprofiling of mouse retinal stem cells. Lab on a Chip. 21(22): 4464-4476.http:\/\/dx.doi.org\/DOI:10.1039\/d1lc00790d<\/a>

Gris\u00e9 KN, Bautista NX, Jacques-Smith K, Coles BLK, van der Kooy D. (2021). Glucocorticoid agonistsenhance retinal stem cell self-renewal and proliferation. Stem Cell Research & Therapy. 12(1): 83.http:\/\/dx.doi.org\/10.1186\/s13287-021-02136-9<\/a>

Ballios BG, Khalili S, Shoichet MS, van der Kooy D. (2019). Induction of Rod and Cone Photoreceptor-Specific Progenitors from Stem Cells. Adv Exp Med Biol. 1185:551-555.https:\/\/doi.org\/10.1007\/978-3-030-27378-1_90<\/a>

Sachewsky N, Xu W, Fuehrmann T, van der Kooy D, Morshead CM. (2019). Lineage tracing reveals the hierarchical relationship between neural stem cell populations in the mouse forebrain. Sci Rep. 9(1):17730.https:\/\/doi.org\/10.1038\/s41598-019-54143-9<\/a>

Shakiba N, Fahmy A, Jayakumaran G, McGibbon S, David L, Trcka D, Elbaz J, Puri MC, Nagy A, van der Kooy D, Goyal S, Wrana JL, Zandstra PW. (2019). Cell competition during reprogramming gives rise to dominant clones. Science. 364(6438):eaan0925.\u00a0https:\/\/doi.org\/10.1126\/science.aan0925<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\nBrokhman I, Xu J, Coles BLK, Razavi R, Engert S, Lickert H, Babona-Pilipos R, Morshead CM, Sibley E, Chen C, van der Kooy D. (2019). Dual embryonic origin of the mammalian enteric nervous system. Dev Biol. 445(2):256-270.\u00a0https:\/\/doi.org\/10.1016\/j.ydbio.2018.11.014<\/a>\n\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>
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2020 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Yee M, Maal-Bared G, Ting-A-Kee R, Chwalek M, Mackay-Clackett I, Bergamini M, Grieder T, van der Kooy D. (2020). Segregation of caffeine reward and aversion in the rat nucleus accumbens shell versuscore. European Journal of Neuroscience. 52(3): 3074-3086.http:\/\/dx.doi.org\/doi: 10.1111\/ejn.14718<\/a>

Ahuja AS, Mothe A, Khazaei M, Badhiwala J, Gilbert EA, van der Kooy D, Morshead CM, Tator C, Fehlings M. (2020). The leading edge – emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury. Stem Cells Translational Medicine. 9: 1509-1530.https:\/\/doi.org\/10.1002\/sctm.19-0135<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\nMitrousis N, Hacibekiroglu S, Ho M, Sauv\u00e9 Y, Nagy A, van der Kooy D, Shoichet MS. (2020). Hydrogel mediated co-transplantation of retinal pigmented epithelium and photoreceptors restores vision in an animal model of advanced retinal degeneration. Biomaterials. 257: 120233.http:\/\/dx.doi.org\/10.1016\/j.biomaterials.2020.120233<\/a>

DeVeale B, van der Kooy D. (2020). Parental bias has benefits. Neuron. 107(6): 1160\u20131179.http:\/\/dx.doi.org\/\/10.1016\/j.neuron.2020.08.023<\/a>\n\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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2019 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Wolfe GS, Tong VW, Merritt DM, Stegeman GW, Flibotte S, van der Kooy D. (2019). A receptor tyrosine kinase plays separate roles in sensory integration and associative learning in C. elegans. eNeuro. 6(4): ENEURO.0244-18.2019.http:\/\/dx.doi.org\/10.1523\/ENEURO.0244-18.2019<\/a>

Grieder TE, Besson M, Maal-Bared G, Pons S, Maskos U, van der Kooy D. (2019). \u03b22* nAChRs onVTA dopamine and GABA neurons separately mediate nicotine aversion and reward. PNAS. 116(51):25968-25973.http:\/\/dx.doi.org\/10.1073\/pnas.1908724116<\/a>

Merritt D, Melkis JG, Kwok B, Tran C, van der Kooy D. (2019). Analysis of mutants suggests Kaminblocking in C. elegans is due to interference with memory recall rather than storage. Scientific Reports.9(1): 2371.http:\/\/dx.doi.org\/10.1038\/s41598-019-38939-3<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\n\nBaakdhah T, van der Kooy D. (2019). Expansion of retinal stem cells and their progeny using cell microcarriers in a bioreactor. Biotechnology Progress. 35(3): e2800.http:\/\/dx.doi.org\/10.1002\/btpr.2800<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Rumajogee P, Altamentova S, Li L, Li J, Wang J, Kuurstra A, Khazaei M, Beldick S, Menon RS, van derKooy D, Fehlings MG. (2018). Exogenous neural precursor cell transplantation results in structural andfunctional recovery in a hypoxic-ischemic hemiplegic mouse model. eNeuro. 5(5): ENEURO.0369-18.2018.http:\/\/dx.doi.org\/10.1523\/ENEURO.0369-18.2018<\/a>

Li N, van der Kooy D. (2018). Mutations in the guanylate cyclase gcy-28 neuronally dissociate naiveattraction and memory retrieval. European Journal of Neuroscience. 48(11): 3367-3378.http:\/\/dx.doi.org\/10.1111\/ejn.14221<\/a>

Khalili S, Ballios B, Belair-Hickey J, Donaldson L, Liu J, Coles B, Gris\u00e9 K, Bader G, Wallace V, Bernier G, Shoichet M, van der Kooy D. (2018). Induction of rod versus cone photoreceptor-specific progenitors from retinal precursor cells. Stem Cell Research. 33: 215-227.http:\/\/dx.doi.org\/doi: 10.1016\/j.scr.2018.11.005<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Gomis S, Labib M, Coles BLK, van der Kooy D, Sargent EH, Kelley SO. (2018). Single-cell tumblingenables high-resolution size profiling of retinal stem cells. ACS Applied Materials & Interfaces. 10:34811-34816.\u00a0http:\/\/dx.doi.org\/10.1021\/acsami.8b10513<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2017 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Grieder TE, Besson M, Maskos U, van der Kooy D. (2017). Deletion of \u03b15 nicotine receptor subunitsabolishes nicotinic aversive motivational effects in a manner that phenocopies dopamine receptorantagonism. European Journal of Neuroscience. 46(1): 1673-1681.https:\/\/doi.org\/10.1111\/ejn.13605<\/a>

Coles-Takabe, B., van der Kooy, D. (2017). P-Cadherin is necessary for retinal stem cell behavior in vitro, but not in vivo. Stem Cell Research. 21: 141-147.https:\/\/doi.org\/10.1016\/j.scr.2017.05.001<\/a>

Reeve RL, Yammine SZ, Morshead CM, van der Kooy D. (2017). Quiescent Oct4+<\/sup>\u00a0Neural Stem Cells (NSCs) Repopulate Ablated Glial Fibrillary Acidic Protein+<\/sup>\u00a0NSCs in the Adult Mouse Brain. Stem Cells. 35(9):2071-2082.\u00a0https:\/\/doi.org\/10.1002\/stem.2662<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Vargas-Perez H, Grieder TE, Ting-A-Kee R, Maal-Bared G, Chwalek M, van der Kooy D. (2017). A single administration of the hallucinogen, 4-acetoxy-dimethyltryptamine, prevents the shift to a drug-dependent state and the expression of withdrawal aversions in rodents. Eur J Neurosci. 45(11):1410-1417.\u00a0https:\/\/doi.org\/10.1111\/ejn.13572<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2016 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Fu\u0308hrmann, T., Tam, RY., Ballarin, B., Coles, B., Elliott Donaghue, I., van der Kooy, D., Nagy, A., Tator,CH., Morshead, CM,. Shoichet, MS. (2016). Injectable hydrogel promotes early survival of inducedpluripotent stem cell-derived oligodendrocytes and attenuates long-term teratoma formation in a spinal cord injury model. Biomaterials. 83: 23-36.https:\/\/doi.org\/10.1016\/j.biomaterials.2015.12.032<\/a>

Huroy S, Kanawaty A, Magomedova L, Cummins CL, George SR, van der Kooy D, Henderson JT. (2016). EphB2 reverse signaling regulates learned opiate tolerance via hippocampal function. Behavioral Brain Research. 308(244): 85-96.https:\/\/doi.org\/10.1016\/j.bbr.2015.09.023<\/a>

Umebayashi D, Coles B, van der Kooy D. (2016). Enrichment of Oligodendrocyte Progenitors from Differentiated Neural Precursors by Clonal Sphere Preparations. Stem Cells Dev. 25(9):712-28. \u00a0https:\/\/doi.org\/10.1089\/scd.2015.0244<\/a>

\u200d<\/a>Reeve RL, Yammine SZ, DeVeale B, van der Kooy D. (2016). Targeted activation of primitive neural stem cells in the mouse brain. Eur J Neurosci. 43(11):1474-85.\u00a0https:\/\/doi.org\/10.1111\/ejn.1322<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Mitrousis N, Tam RY, Baker AEG, van der Kooy D, Shoichet MS. Hyaluronic acid-based hydrogels enable rod photoreceptor survival and maturation in vitro through activation of the mTOR pathway Advanced Functional Materials. 26 (2016) 1975-85.\u00a0https:\/\/doi.org\/10.1002\/adfm.201504024<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2015 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Ballios BG, Cooke MJ, Donaldson L, Coles BL, Morshead CM, van der Kooy D, Shoichet MS. (2015). Ahyaluronan-based injectable hydrogel improves the survival and integration of stem cell progeny following transplantation. Stem Cell Reports. 4(6): 1031-1045.https:\/\/doi.org\/10.1016\/j.stemcr.2015.04.008<\/a>

Babak T, DeVeale B, Tsang EK, Zhou Y, Li X, Smith KS, Kukurba KR, Zhang R, Li JB, van der Kooy D, Montgomery SB, Fraser HB. (2015). Genetic conflict reflected in tissue-specific maps of genomic imprinting in human and mouse. Nature Genetics. 47(5): 544-549.https:\/\/doi.org\/10.1038\/ng.3274<\/a>

Razavi R, Najafabadi HS, Abdullah S, Smukler S, Arntfield M, van der Kooy D. (2015). Diabetes enhances the proliferation of adult pancreatic multipotent progenitor cells and biases their differentiation to more \u03b2-cell production. Diabetes. 4(64): 1311-1323.https:\/\/doi.org\/10.2337\/db14-0070<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Ting-A-Kee R, Heinmiller A, van der Kooy D. (2015). A proposed resolution to the paradox of drug reward: Dopamine’s evolution from an aversive signal to a facilitator of drug reward via negative reinforcement. Neurosci Biobehav Rev. 56:50-61.\u00a0https:\/\/doi.org\/10.1016\/j.neubiorev.2015.06.016<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2014 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Sachewsky N, Rose KL, Yu F, Leeder R, Xu W, van der Kooy D, Morshead CM. (2014). Primitive neural stem cells in the adult mammalian brain give rise to GFAP-expressing neural stem cells. Stem Cell Reports. 2(6): 810-824.https:\/\/doi.org\/10.1016\/j.stemcr.2014.04.008<\/a>

Greider T, Vargas-Perez H, Herman M, Contet C, Tan L, Freiling J, Clarke L, Crawford E, Koebel P, Roberto M, Kieffer BL, Sawchenko PE, Koob GF, van der Kooy D, George O. (2014). VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation. Nature Neuroscience. 17(12): 1751-1758.https:\/\/doi.org\/10.1038\/nn.3872<\/a>

Michael IP, Westenskow PD, Hacibekiroglu S, Greenwald AC, Ballios BG, Kurihara T, Li Z, WarrenCM, Zhang P, Aguilar E, Donaldson L, Marchetti V, Baba T, Hussein SM, Sung HK, Iruela-ArispeML, Rini JM, van der Kooy D, Friedlander M, Nagy A. (2014). Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye. EMBO molecular medicine. 6(5): 604-623.https:\/\/doi.org\/10.1002\/emmm.201303708<\/a>

Vargas-Perez H, Bahi A, Bufalino MR, Ting-A-Kee R, Maal-Bared G, Lam J, Fahmy A, Clarke L, Blanchard JK, Larsen BR, Steffensen S, Dreyer JL, van der Kooy D. (2014). BDNF signaling in the VTA links the drug-dependent state to drug withdrawal aversions. J Neurosci. 34(23):7899-909. \u00a0https:\/\/doi.org\/10.1523\/jneurosci.3776-13.2014<\/a>

Bufalino MR, van der Kooy D. (2014). The aggregation and inheritance of damaged proteins determines cell fate during mitosis. Cell Cycle. 13(7):1201-7.\u00a0https:\/\/doi.org\/10.4161\/cc.28106<\/a>

Teichert AM, Pereira S, Coles B, Chaddah R, Runciman S, Brokhman I, van der Kooy D. (2014). The neural stem cell lineage reveals novel relationships among spermatogonial germ stem cells and other pluripotent stem cells. Stem Cells Dev. 23(7):767-78.\u00a0https:\/\/doi.org\/10.1089\/scd.2013.0245<\/a>

Balenci L, van der Kooy D. (2014). Notch signaling induces retinal stem-like properties in perinatal neural retina progenitors and promotes symmetric divisions in adult retinal stem cells. Stem Cells Dev. 23(3):230-44.\u00a0https:\/\/doi.org\/10.1089\/scd.2013.0177<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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DeVeale B, Bausch-Fluck D, Seaberg R, Runciman S, Akbarian V, Karpowicz P, Yoon C, Song H, Leeder R, Zandstra PW, Wollscheid B, van der Kooy D. (2014). Surfaceome profiling reveals regulators of neural stem cell function. Stem Cells. 32(1):258-68.\u00a0https:\/\/doi.org\/10.1002\/stem.1550<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2013 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Salewski RP, Buttigieg J, Mitchell RA, van der Kooy D, Nagy A, Fehlings MG. (2013). The generation of definitive neural stem cells from PiggyBac transposon-induced pluripotent stem cells can be enhanced by induction of the NOTCH signaling pathway.Stem Cells and Development. 22(3): 383-396.https:\/\/doi.org\/10.1089\/scd.2012.0218<\/a>

Pereira S, van der Kooy D. (2013). Entwined engrams: The evolution of associative and non-associative learning. Worm. 2(2):e22725.https:\/\/doi.org\/10.4161\/worm.22725<\/a>

DeVeale B, Brokhman I, Mohseni P, Babak T, Yoon C, Lin A, Onishi K, Tomilin A, Pevny L, Zandstra PW, Nagy A, van der Kooy D. (2013). Oct4 is required ~E7.5 for proliferation in the primitive streak. PLoS Genet. 9(11):e1003957.\u00a0https:\/\/doi.org\/10.1371\/journal.pgen.1003957<\/a>\u00a0\u00a0

Holowacz T, Alexson TO, Coles BL, Doble BW, Kelly KF, Woodgett JR, Van Der Kooy D. (2013). \u00a0The responses of neural stem cells to the level of GSK-3 depend on the tissue of origin. Biol Open. 2(8):812-21.\u00a0https:\/\/doi.org\/10.1242\/bio.20131941<\/a>

Balenci L, Wonders C, Coles BL, Clarke L, van der Kooy D. (2013). \u00a0Bone morphogenetic proteins and secreted frizzled related protein 2 maintain the quiescence of adult mammalian retinal stem cells. Stem Cells. 31(10):2218-30.https:\/\/doi.org\/10.1002\/stem.1470<\/a>

Riad-Allen L, van der Kooy D. (2013). \u00a0Social defeat stress switches the neural system mediating benzodiazepine conditioned motivation. Behav Neurosci. 127(4):515-23.https:\/\/doi.org\/10.1037\/a0032962<\/a>

Bufalino MR, DeVeale B, van der Kooy D. (2013). \u00a0The asymmetric segregation of damaged proteins is stem cell-type dependent. J Cell Biol. 201(4):523-30.https:\/\/doi.org\/10.1083\/jcb.201207052<\/a>

Ting-A-Kee R, Mercuriano LE, Vargas-Perez H, George SR, van der Kooy D. (2013). \u00a0Dopamine D1 receptors are not critical for opiate reward but can mediate opiate memory retrieval in a state-dependent manner. Behav Brain Res. 247:174-177.\u00a0https:\/\/doi.org\/10.1016\/j.bbr.2013.03.026<\/a>

Arntfield M, van der Kooy D. (2013). \u00a0The adult mammalian pancreas contains separate precursors of pancreatic and neural crest developmental origins. Stem Cells Dev. 22(15):2145-57.\u00a0https:\/\/doi.org\/10.1089\/scd.2013.0027<\/a>

Ting-A-Kee R, Vargas-Perez H, Mabey JK, Shin SI, Steffensen SC, van der Kooy D. (2013). Ventral tegmental area GABA neurons and opiate motivation. Psychopharmacology (Berl). 227(4):697-709.\u00a0https:\/\/doi.org\/10.1007\/s00213-013-3002-3<\/a>\u00a0\u200d
Sellings L, Pereira S, Qian C, Dixon-McDougall T, Nowak C, Zhao B, Tyndale RF, van der Kooy D. (2013). Nicotine-motivated behavior in Caenorhabditis elegans requires the nicotinic acetylcholine receptor subunits acr-5 and acr-15. Eur J Neurosci. 37(5):743-56.https:\/\/doi.org\/10.1111\/ejn.12099<\/a>

Ballios BG, Marigo V, van der Kooy D. Directed differentiation of retinal stem cells into photoreceptors and retinal pigment epithelium. In Kaur N, Vemuri M (Eds.), Neural Stem Cell Assays. Wiley-Blackwell, New Jersey, 2013.http:\/\/dx.doi.org\/10.1002\/9781118308295.ch14<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Ting-A-Kee R, Vargas-Perez H, Bufalino MR, Bahi A, Dreyer JL, Tyndale RF, van der Kooy D. Infusion of brain-derived neurotrophic factor into the ventral tegmental area switches the substrates mediating ethanol motivation. Euoropean Journal of Neuroscience. 37(6) (2013) 996-1003.https:\/\/doi.org\/10.1111\/ejn.12105<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2012 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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DeVeale B, van der Kooy D, Babak T. (2012). Critical evaluation of imprinted gene expression by RNASeq: a new perspective. PLoS Genetics. 8: e1002600.https:\/\/doi.org\/10.1371\/journal.pgen.1002600<\/a>

Pereira S, van der Kooy D. (2012). Two forms of learning following training to a single odorant in Caenorhabditis elegans AWC neurons. J Neurosci. 32(26):9035-44.\u00a0https:\/\/doi.org\/10.1523\/jneurosci.4221-11.2012<\/a>

Chaddah R, Arntfield M, Runciman S, Clarke L, van der Kooy D. (2012). Clonal neural stem cells from human embryonic stem cell colonies. J Neurosci. 32(23):7771-81.\u00a0https:\/\/doi.org\/10.1523\/jneurosci.3286-11.2012<\/a>

Clarke L, Ballios BG, van der Kooy D. (2012). Generation and clonal isolation of retinal stem cells from human embryonic stem cells. Eur J Neurosci. 36(1):1951-9.\u00a0https:\/\/doi.org\/10.1111\/j.1460-9568.2012.08123.x<\/a>

Grieder TE, George O, Tan H, George SR, Le Foll B, Laviolette SR, van der Kooy D. (2012). Phasic D1 and tonic D2 dopamine receptor signaling double dissociate the motivational effects of acute nicotine and chronic nicotine withdrawal. Proc Natl Acad Sci U S A. 109(8):3101-6.https:\/\/doi.org\/10.1073\/pnas.1114422109<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Ballios, B., Clarke, L., Shoichet, M., van der Kooy, D. The adult retinal stem cell is a rare pigmented cell in the ciliary epithelium that can differentiate into photoreceptors. Biology Open (2012) 1:237-246.https:\/\/doi.org\/10.1242\/bio.2012027<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2011 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Pacey LK, Doss L, Cifelli C, van der Kooy D, Heximer SP, Hampson DR. (2011). Genetic deletion ofregulator of G-protein signaling 4 (RGS4) rescues a subset of fragile X related phenotypes in the FMR1knockout mouse. Molecular and Cellular Neurosciences. 46(3): 563-572.https:\/\/doi.org\/10.1016\/j.mcn.2010.12.005<\/a>

Akers KG, Kushner SA, Leslie AT, Clarke L, van der Kooy D, Lerch JP, Frankland PW. (2011). Fetalalcohol exposure leads to abnormal olfactory bulb development and impaired odor discrimination in adultmice. Molecular Brain. 4(29): 1-15.https:\/\/doi.org\/10.1186\/1756-6606-4-29<\/a>

Wu L, Lam S, Cao H, Guan R, Duan R, van der Kooy D, Bremner R, Molday RS, Hu J. (2011).Subretinal gene delivery using helper-dependent adenoviral vectors. Cell & Bioscience. 1(15): 1-7.https:\/\/doi.org\/10.1186\/2045-3701-1-15<\/a>

Clarke L, van der Kooy D. (2011). The adult mouse dentate gyrus contains populations of committed progenitor cells that are distinct from subependymal zone neural stem cells. Stem Cells. 29(9):1448-58.\u00a0https:\/\/doi.org\/10.1002\/stem.692<\/a>

Arntfield ME, van der Kooy D. (2011). \u03b2-Cell evolution: How the pancreas borrowed from the brain: The shared toolbox of genes expressed by neural and pancreatic endocrine cells may reflect their evolutionary relationship. Bioessays. 33(8):582-7.\u00a0https:\/\/doi.org\/10.1002\/bies.201100015<\/a>

Rowland JW, Lee JJ, Salewski RP, Eftekharpour E, van der Kooy D, Fehlings MG. (2011). Generation of neural stem cells from embryonic stem cells using the default mechanism: in vitro and in vivo characterization. Stem Cells Dev. 20(11):1829-45.\u00a0https:\/\/doi.org\/10.1089\/scd.2011.0214<\/a>

Holowacz T, Huelsken J, Dufort D, van der Kooy D. (2011). Neural stem cells are increased after loss of \u03b2-catenin, but neural progenitors undergo cell death. Eur J Neurosci. 33(8):1366-75.https:\/\/doi.org\/10.1111\/j.1460-9568.2011.07632.x<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Smukler SR, Arntfield ME, Razavi R, Bikopoulos G, Karpowicz P, Seaberg R, Dai F, Lee S, Ahrens R, Fraser PE, Wheeler MB, van der Kooy D. (2011). The adult mouse and human pancreas contain rare multipotent stem cells that express insulin. Cell Stem Cell. 8(3):281-93.\u00a0https:\/\/doi.org\/10.1016\/j.stem.2011.01.015<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2010 Publications<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Coles BL, van der Kooy D. (2010). Isolation of retinal stem cells from the mouse eye. J Vis Exp. 43: pii:2209.\u00a0http:\/\/dx.doi.org\/10.3791\/2209.<\/a>

Ballios BG, van der Kooy D. (2010). Biology and therapeutic potential of adult retinal stem cells. Can J Ophthalmol. 45(4):342-51.\u00a0https:\/\/doi.org\/10.3129\/i10-070<\/a>

Sturgess JE, Ting-A-Kee RA, Podbielski D, Sellings LH, Chen JF, van der Kooy D. (2010). Adenosine A1 and A2A receptors are not upstream of caffeine’s dopamine D2 receptor-dependent aversive effects and dopamine-independent rewarding effects. Eur J Neurosci. 32(1):143-54.https:\/\/doi.org\/10.1111\/j.1460-9568.2010.07247.x<\/a>

Lin CH, Tomioka M, Pereira S, Sellings L, Iino Y, van der Kooy D. (2010). Insulin signaling plays a dual role in Caenorhabditis elegans memory acquisition and memory retrieval. J Neurosci. 30(23):8001-11.\u00a0https:\/\/doi.org\/10.1523\/jneurosci.4636-09.2010<\/a>

Hoffmann MC, Sellings LH, van der Kooy D. (2010). A diacetyl-induced quiescence in young Caenorhabditis elegans. Behav Brain Res. 214(1):12-7.\u00a0https:\/\/doi.org\/10.1016\/j.bbr.2010.05.021<\/a>

Ballios BG, Cooke MJ, van der Kooy D, Shoichet MS. (2010). A hydrogel-based stem cell delivery system to treat retinal degenerative diseases. Biomaterials. 31(9):2555-64.\u00a0https:\/\/doi.org\/10.1016\/j.biomaterials.2009.12.004<\/a>

Grieder TE, Sellings LH, Vargas-Perez H, Ting-A-Kee R, Siu EC, Tyndale RF, van der Kooy D. (2010). Dopaminergic signaling mediates the motivational response underlying the opponent process to chronic but not acute nicotine. Neuropsychopharmacology. 35(4):943-54.\u00a0https:\/\/doi.org\/10.1038\/npp.2009.198<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Inoue T, Coles BL, Dorval K, Bremner R, Bessho Y, Kageyama R, Hino S, Matsuoka M, Craft CM, McInnes RR, Tremblay F, Prusky GT, van der Kooy D. (2010). Maximizing functional photoreceptor differentiation from adult human retinal stem cells. Stem Cells. 28(3):489-500.\u00a0https:\/\/doi.org\/10.1002\/stem.279<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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For Earlier Publications: Click Here<\/a><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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2024 Publications<\/h2><\/div>

Maal-Bared, G., \u00a0Yee, M., \u00a0Harding, E. K., \u00a0Ghebreselassie, M., \u00a0Bergamini, M., \u00a0Choy, R., \u00a0Kim, E., \u00a0Di Vito, S., Patel, M., \u00a0Amirzadeh, M., \u00a0Grieder, T. E., \u00a0Coles, B. L., \u00a0Nagy, J. I., \u00a0Bonin, R. P., \u00a0Steenland, H. W., & \u00a0D.van der Kooy (2024). \u00a0Connexin-36-positive gap junctions in ventral tegmental area GABA neurons sustain opiate dependence. European Journal of Neuroscience, \u00a059(12), \u00a03422\u20133444.\u00a0https:\/\/doi.org\/10.1111\/ejn.16366
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\u200d<\/em><\/a>Mokady D, Charish J, Barretto-Burns P, Gris\u00e9 KN, Coles BLK, Raab S, Ortin-Martinez A, Mu\u0308ller A,Fasching B, Jain P, Drukker M, van der Kooy D, Steger M. (2024). Small-Molecule-Directed Endogenous Regeneration of Visual Function in a Mammalian Retinal Degeneration Model. International Journal of Molecular Sciences. 25(3): 1521-1539.http:\/\/dx.doi.org\/10.3390\/ijms25031521<\/a>
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Vargas-Perez H, Minauro-Sanmiguel F, Ting-A-Kee R, Grieder TE, M\u00e9ndez-D\u00edaz M, Prosp\u00e9ro-Garc\u00eda O, van der Kooy D. Rewarding Effects of the Hallucinogen 4-AcO-DMT Administration and Withdrawal in Rats: A Challenge to the Opponent-Process Theory. Neurosci Lett. 2024 Jan 18;820:137597.\u00a0doi: 10.1016\/j.neulet.2023.137597<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2023 Publications<\/h2><\/div>

Vargas-Perez H, Grieder T, van der Kooy D (van der Kooy's h-index 104). (2023). Neural plasticity in theventral tegmental area, aversive motivation during drug withdrawal and hallucinogenic therapy. Journal of Psychoactive Drugs. 55(1): 62-72.https:\/\/doi.org\/10.1080\/02791072.2022.2033889<\/a>

Yammine S, Burns I, Gosio J, Peluso A, Merritt D, Innes B, Coles B, Yan WR, Bader GD, Morshead C, van der Kooy D. (2023). Fate specification of GFAP-negative primitive neural stem cells and their progeny at clonal resolution. Stem Cells and Development.https:\/\/doi.org\/10.1089\/scd.2023.0038<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2022 Publications<\/h2><\/div>

Merritt DM, MacKay-Clackett I, Almeida SMT, Tran C, Ansar S, van der Kooy D. (2022). Arrestin-mediated Desensitization Enables Olfactory Discrimination in C. elegans. PNAS. 119(31): e2116957119.http:\/\/dx.doi.org\/doi:10.1073\/pnas.2116957119<\/a>

Grieder TE, Yee M, Vargas-Perez H, Maal-Bared G, George S, Ting-A-Kee R, George O, van der Kooy D. (2022). Administration of BDNF in the ventral tegmental area produces a switch from a nicotine-nondependent D1R-mediated motivational state to a nicotine-dependent-like D2R-mediated motivational state. European Journal of Neuroscience. 55(3): 714-724.https:\/\/doi.org\/10.1111\/ejn.15579<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2021 Publications<\/h2><\/div>

Gris\u00e9 KN, Coles BLK, Bautista NX, van der Kooy D. (2021). Activation of adult mammalian retinal stemcells in vivo via antagonism of BMP and sFRP2. Stem Cell Research & Therapy. 12(1): 560.\u00a0https:\/\/doi.org\/10.1186\/s13287-021-02630-0<\/a>

Adams K, Neemat M, Green-Holland M, Vonderwalde I, Umebayashi D, Sachewsky N, Coles BLK, vander Kooy D, Morshead CM. (2021). Constraint-induced movement therapy promotes motor recovery afterneonatal stroke in the absence of neural precursor activation. European Journal of Neuroscience. 53(4):1334:1349.http:\/\/dx.doi.org\/doi.org\/10.1111\/ejn.14993<\/a>

Baker AEG, Cui H, Ballios BG, Ing S, Yan P, Wolfer J, Wright T, Dang M, Gan NY, Cooke MJ, Ort\u00edn-Mart\u00ednez A, Wallace VA, van der Kooy D, Devenyi R, Shoichet MS. (2021). Stable oxime-crosslinked hyaluronan-based hydrogel as a biomimetic vitreous substitute. Biomaterials. 271: 120750.https:\/\/doi.org\/10.1016\/j.biomaterials.2021.120750<\/a>

Baakdhah TW, Coles BL, van der Kooy S. (2021). A defined subset of clonal retinal stem cell spheres isbiased to RPE differentiation. iScience. 24(6): 102574.https:\/\/doi.org\/10.1016\/j.isci.2021.102574<\/a>

Coles BLK, Labib M, Poudineh M, Innes BT, Belair-Hickey J, Gomis S, Wang Z, Bader GD, SargentEH, Kelley OS, van der Kooy D. (2021). A microfluidic platform enables comprehensive gene expressionprofiling of mouse retinal stem cells. Lab on a Chip. 21(22): 4464-4476.http:\/\/dx.doi.org\/DOI:10.1039\/d1lc00790d<\/a>

Gris\u00e9 KN, Bautista NX, Jacques-Smith K, Coles BLK, van der Kooy D. (2021). Glucocorticoid agonistsenhance retinal stem cell self-renewal and proliferation. Stem Cell Research & Therapy. 12(1): 83.http:\/\/dx.doi.org\/10.1186\/s13287-021-02136-9<\/a>

Ballios BG, Khalili S, Shoichet MS, van der Kooy D. (2019). Induction of Rod and Cone Photoreceptor-Specific Progenitors from Stem Cells. Adv Exp Med Biol. 1185:551-555.https:\/\/doi.org\/10.1007\/978-3-030-27378-1_90<\/a>

Sachewsky N, Xu W, Fuehrmann T, van der Kooy D, Morshead CM. (2019). Lineage tracing reveals the hierarchical relationship between neural stem cell populations in the mouse forebrain. Sci Rep. 9(1):17730.https:\/\/doi.org\/10.1038\/s41598-019-54143-9<\/a>

Shakiba N, Fahmy A, Jayakumaran G, McGibbon S, David L, Trcka D, Elbaz J, Puri MC, Nagy A, van der Kooy D, Goyal S, Wrana JL, Zandstra PW. (2019). Cell competition during reprogramming gives rise to dominant clones. Science. 364(6438):eaan0925.\u00a0https:\/\/doi.org\/10.1126\/science.aan0925<\/a>

Brokhman I, Xu J, Coles BLK, Razavi R, Engert S, Lickert H, Babona-Pilipos R, Morshead CM, Sibley E, Chen C, van der Kooy D. (2019). Dual embryonic origin of the mammalian enteric nervous system. Dev Biol. 445(2):256-270.\u00a0https:\/\/doi.org\/10.1016\/j.ydbio.2018.11.014<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2020 Publications<\/h2><\/div>

Yee M, Maal-Bared G, Ting-A-Kee R, Chwalek M, Mackay-Clackett I, Bergamini M, Grieder T, van der Kooy D. (2020). Segregation of caffeine reward and aversion in the rat nucleus accumbens shell versuscore. European Journal of Neuroscience. 52(3): 3074-3086.http:\/\/dx.doi.org\/doi: 10.1111\/ejn.14718<\/a>

Ahuja AS, Mothe A, Khazaei M, Badhiwala J, Gilbert EA, van der Kooy D, Morshead CM, Tator C, Fehlings M. (2020). The leading edge - emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury. Stem Cells Translational Medicine. 9: 1509-1530.https:\/\/doi.org\/10.1002\/sctm.19-0135<\/a>

Mitrousis N, Hacibekiroglu S, Ho M, Sauv\u00e9 Y, Nagy A, van der Kooy D, Shoichet MS. (2020). Hydrogel mediated co-transplantation of retinal pigmented epithelium and photoreceptors restores vision in an animal model of advanced retinal degeneration. Biomaterials. 257: 120233.http:\/\/dx.doi.org\/10.1016\/j.biomaterials.2020.120233<\/a>

DeVeale B, van der Kooy D. (2020). Parental bias has benefits. Neuron. 107(6): 1160\u20131179.http:\/\/dx.doi.org\/\/10.1016\/j.neuron.2020.08.023<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2019 Publications<\/h2><\/div>

Wolfe GS, Tong VW, Merritt DM, Stegeman GW, Flibotte S, van der Kooy D. (2019). A receptor tyrosine kinase plays separate roles in sensory integration and associative learning in C. elegans. eNeuro. 6(4): ENEURO.0244-18.2019.http:\/\/dx.doi.org\/10.1523\/ENEURO.0244-18.2019<\/a>

Grieder TE, Besson M, Maal-Bared G, Pons S, Maskos U, van der Kooy D. (2019). \u03b22* nAChRs onVTA dopamine and GABA neurons separately mediate nicotine aversion and reward. PNAS. 116(51):25968-25973.http:\/\/dx.doi.org\/10.1073\/pnas.1908724116<\/a>

Merritt D, Melkis JG, Kwok B, Tran C, van der Kooy D. (2019). Analysis of mutants suggests Kaminblocking in C. elegans is due to interference with memory recall rather than storage. Scientific Reports.9(1): 2371.http:\/\/dx.doi.org\/10.1038\/s41598-019-38939-3<\/a>

Baakdhah T, van der Kooy D. (2019). Expansion of retinal stem cells and their progeny using cell microcarriers in a bioreactor. Biotechnology Progress. 35(3): e2800.http:\/\/dx.doi.org\/10.1002\/btpr.2800<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2018 Publications<\/h2><\/div>

Rumajogee P, Altamentova S, Li L, Li J, Wang J, Kuurstra A, Khazaei M, Beldick S, Menon RS, van derKooy D, Fehlings MG. (2018). Exogenous neural precursor cell transplantation results in structural andfunctional recovery in a hypoxic-ischemic hemiplegic mouse model. eNeuro. 5(5): ENEURO.0369-18.2018.http:\/\/dx.doi.org\/10.1523\/ENEURO.0369-18.2018<\/a>

Li N, van der Kooy D. (2018). Mutations in the guanylate cyclase gcy-28 neuronally dissociate naiveattraction and memory retrieval. European Journal of Neuroscience. 48(11): 3367-3378.http:\/\/dx.doi.org\/10.1111\/ejn.14221<\/a>

Khalili S, Ballios B, Belair-Hickey J, Donaldson L, Liu J, Coles B, Gris\u00e9 K, Bader G, Wallace V, Bernier G, Shoichet M, van der Kooy D. (2018). Induction of rod versus cone photoreceptor-specific progenitors from retinal precursor cells. Stem Cell Research. 33: 215-227.http:\/\/dx.doi.org\/doi: 10.1016\/j.scr.2018.11.005<\/a>

Gomis S, Labib M, Coles BLK, van der Kooy D, Sargent EH, Kelley SO. (2018). Single-cell tumblingenables high-resolution size profiling of retinal stem cells. ACS Applied Materials & Interfaces. 10:34811-34816.\u00a0http:\/\/dx.doi.org\/10.1021\/acsami.8b10513<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2017 Publications<\/h2><\/div>

Grieder TE, Besson M, Maskos U, van der Kooy D. (2017). Deletion of \u03b15 nicotine receptor subunitsabolishes nicotinic aversive motivational effects in a manner that phenocopies dopamine receptorantagonism. European Journal of Neuroscience. 46(1): 1673-1681.https:\/\/doi.org\/10.1111\/ejn.13605<\/a>

Coles-Takabe, B., van der Kooy, D. (2017). P-Cadherin is necessary for retinal stem cell behavior in vitro, but not in vivo. Stem Cell Research. 21: 141-147.https:\/\/doi.org\/10.1016\/j.scr.2017.05.001<\/a>

Reeve RL, Yammine SZ, Morshead CM, van der Kooy D. (2017). Quiescent Oct4+<\/sup>\u00a0Neural Stem Cells (NSCs) Repopulate Ablated Glial Fibrillary Acidic Protein+<\/sup>\u00a0NSCs in the Adult Mouse Brain. Stem Cells. 35(9):2071-2082.\u00a0https:\/\/doi.org\/10.1002\/stem.2662<\/a>
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Vargas-Perez H, Grieder TE, Ting-A-Kee R, Maal-Bared G, Chwalek M, van der Kooy D. (2017). A single administration of the hallucinogen, 4-acetoxy-dimethyltryptamine, prevents the shift to a drug-dependent state and the expression of withdrawal aversions in rodents. Eur J Neurosci. 45(11):1410-1417.\u00a0https:\/\/doi.org\/10.1111\/ejn.13572<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2016 Publications<\/h2><\/div>

Fu\u0308hrmann, T., Tam, RY., Ballarin, B., Coles, B., Elliott Donaghue, I., van der Kooy, D., Nagy, A., Tator,CH., Morshead, CM,. Shoichet, MS. (2016). Injectable hydrogel promotes early survival of inducedpluripotent stem cell-derived oligodendrocytes and attenuates long-term teratoma formation in a spinal cord injury model. Biomaterials. 83: 23-36.https:\/\/doi.org\/10.1016\/j.biomaterials.2015.12.032<\/a>

Huroy S, Kanawaty A, Magomedova L, Cummins CL, George SR, van der Kooy D, Henderson JT. (2016). EphB2 reverse signaling regulates learned opiate tolerance via hippocampal function. Behavioral Brain Research. 308(244): 85-96.https:\/\/doi.org\/10.1016\/j.bbr.2015.09.023<\/a>

Umebayashi D, Coles B, van der Kooy D. (2016). Enrichment of Oligodendrocyte Progenitors from Differentiated Neural Precursors by Clonal Sphere Preparations. Stem Cells Dev. 25(9):712-28. \u00a0https:\/\/doi.org\/10.1089\/scd.2015.0244<\/a>

\u200d<\/a>Reeve RL, Yammine SZ, DeVeale B, van der Kooy D. (2016). Targeted activation of primitive neural stem cells in the mouse brain. Eur J Neurosci. 43(11):1474-85.\u00a0https:\/\/doi.org\/10.1111\/ejn.1322<\/a>

Mitrousis N, Tam RY, Baker AEG, van der Kooy D, Shoichet MS. Hyaluronic acid-based hydrogels enable rod photoreceptor survival and maturation in vitro through activation of the mTOR pathway Advanced Functional Materials. 26 (2016) 1975-85.\u00a0https:\/\/doi.org\/10.1002\/adfm.201504024<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2015 Publications<\/h2><\/div>

Ballios BG, Cooke MJ, Donaldson L, Coles BL, Morshead CM, van der Kooy D, Shoichet MS. (2015). Ahyaluronan-based injectable hydrogel improves the survival and integration of stem cell progeny following transplantation. Stem Cell Reports. 4(6): 1031-1045.https:\/\/doi.org\/10.1016\/j.stemcr.2015.04.008<\/a>

Babak T, DeVeale B, Tsang EK, Zhou Y, Li X, Smith KS, Kukurba KR, Zhang R, Li JB, van der Kooy D, Montgomery SB, Fraser HB. (2015). Genetic conflict reflected in tissue-specific maps of genomic imprinting in human and mouse. Nature Genetics. 47(5): 544-549.https:\/\/doi.org\/10.1038\/ng.3274<\/a>

Razavi R, Najafabadi HS, Abdullah S, Smukler S, Arntfield M, van der Kooy D. (2015). Diabetes enhances the proliferation of adult pancreatic multipotent progenitor cells and biases their differentiation to more \u03b2-cell production. Diabetes. 4(64): 1311-1323.https:\/\/doi.org\/10.2337\/db14-0070<\/a>

Ting-A-Kee R, Heinmiller A, van der Kooy D. (2015). A proposed resolution to the paradox of drug reward: Dopamine's evolution from an aversive signal to a facilitator of drug reward via negative reinforcement. Neurosci Biobehav Rev. 56:50-61.\u00a0https:\/\/doi.org\/10.1016\/j.neubiorev.2015.06.016<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2014 Publications<\/h2><\/div>

Sachewsky N, Rose KL, Yu F, Leeder R, Xu W, van der Kooy D, Morshead CM. (2014). Primitive neural stem cells in the adult mammalian brain give rise to GFAP-expressing neural stem cells. Stem Cell Reports. 2(6): 810-824.https:\/\/doi.org\/10.1016\/j.stemcr.2014.04.008<\/a>

Greider T, Vargas-Perez H, Herman M, Contet C, Tan L, Freiling J, Clarke L, Crawford E, Koebel P, Roberto M, Kieffer BL, Sawchenko PE, Koob GF, van der Kooy D, George O. (2014). VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation. Nature Neuroscience. 17(12): 1751-1758.https:\/\/doi.org\/10.1038\/nn.3872<\/a>

Michael IP, Westenskow PD, Hacibekiroglu S, Greenwald AC, Ballios BG, Kurihara T, Li Z, WarrenCM, Zhang P, Aguilar E, Donaldson L, Marchetti V, Baba T, Hussein SM, Sung HK, Iruela-ArispeML, Rini JM, van der Kooy D, Friedlander M, Nagy A. (2014). Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye. EMBO molecular medicine. 6(5): 604-623.https:\/\/doi.org\/10.1002\/emmm.201303708<\/a>

Vargas-Perez H, Bahi A, Bufalino MR, Ting-A-Kee R, Maal-Bared G, Lam J, Fahmy A, Clarke L, Blanchard JK, Larsen BR, Steffensen S, Dreyer JL, van der Kooy D. (2014). BDNF signaling in the VTA links the drug-dependent state to drug withdrawal aversions. J Neurosci. 34(23):7899-909. \u00a0https:\/\/doi.org\/10.1523\/jneurosci.3776-13.2014<\/a>

Bufalino MR, van der Kooy D. (2014). The aggregation and inheritance of damaged proteins determines cell fate during mitosis. Cell Cycle. 13(7):1201-7.\u00a0https:\/\/doi.org\/10.4161\/cc.28106<\/a>

Teichert AM, Pereira S, Coles B, Chaddah R, Runciman S, Brokhman I, van der Kooy D. (2014). The neural stem cell lineage reveals novel relationships among spermatogonial germ stem cells and other pluripotent stem cells. Stem Cells Dev. 23(7):767-78.\u00a0https:\/\/doi.org\/10.1089\/scd.2013.0245<\/a>

Balenci L, van der Kooy D. (2014). Notch signaling induces retinal stem-like properties in perinatal neural retina progenitors and promotes symmetric divisions in adult retinal stem cells. Stem Cells Dev. 23(3):230-44.\u00a0https:\/\/doi.org\/10.1089\/scd.2013.0177<\/a>

DeVeale B, Bausch-Fluck D, Seaberg R, Runciman S, Akbarian V, Karpowicz P, Yoon C, Song H, Leeder R, Zandstra PW, Wollscheid B, van der Kooy D. (2014). Surfaceome profiling reveals regulators of neural stem cell function. Stem Cells. 32(1):258-68.\u00a0https:\/\/doi.org\/10.1002\/stem.1550<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2013 Publications<\/h2><\/div>

Salewski RP, Buttigieg J, Mitchell RA, van der Kooy D, Nagy A, Fehlings MG. (2013). The generation of definitive neural stem cells from PiggyBac transposon-induced pluripotent stem cells can be enhanced by induction of the NOTCH signaling pathway.Stem Cells and Development. 22(3): 383-396.https:\/\/doi.org\/10.1089\/scd.2012.0218<\/a>

Pereira S, van der Kooy D. (2013). Entwined engrams: The evolution of associative and non-associative learning. Worm. 2(2):e22725.https:\/\/doi.org\/10.4161\/worm.22725<\/a>

DeVeale B, Brokhman I, Mohseni P, Babak T, Yoon C, Lin A, Onishi K, Tomilin A, Pevny L, Zandstra PW, Nagy A, van der Kooy D. (2013). Oct4 is required ~E7.5 for proliferation in the primitive streak. PLoS Genet. 9(11):e1003957.\u00a0https:\/\/doi.org\/10.1371\/journal.pgen.1003957<\/a>\u00a0\u00a0

Holowacz T, Alexson TO, Coles BL, Doble BW, Kelly KF, Woodgett JR, Van Der Kooy D. (2013). \u00a0The responses of neural stem cells to the level of GSK-3 depend on the tissue of origin. Biol Open. 2(8):812-21.\u00a0https:\/\/doi.org\/10.1242\/bio.20131941<\/a>

Balenci L, Wonders C, Coles BL, Clarke L, van der Kooy D. (2013). \u00a0Bone morphogenetic proteins and secreted frizzled related protein 2 maintain the quiescence of adult mammalian retinal stem cells. Stem Cells. 31(10):2218-30.https:\/\/doi.org\/10.1002\/stem.1470<\/a>

Riad-Allen L, van der Kooy D. (2013). \u00a0Social defeat stress switches the neural system mediating benzodiazepine conditioned motivation. Behav Neurosci. 127(4):515-23.https:\/\/doi.org\/10.1037\/a0032962<\/a>

Bufalino MR, DeVeale B, van der Kooy D. (2013). \u00a0The asymmetric segregation of damaged proteins is stem cell-type dependent. J Cell Biol. 201(4):523-30.https:\/\/doi.org\/10.1083\/jcb.201207052<\/a>

Ting-A-Kee R, Mercuriano LE, Vargas-Perez H, George SR, van der Kooy D. (2013). \u00a0Dopamine D1 receptors are not critical for opiate reward but can mediate opiate memory retrieval in a state-dependent manner. Behav Brain Res. 247:174-177.\u00a0https:\/\/doi.org\/10.1016\/j.bbr.2013.03.026<\/a>

Arntfield M, van der Kooy D. (2013). \u00a0The adult mammalian pancreas contains separate precursors of pancreatic and neural crest developmental origins. Stem Cells Dev. 22(15):2145-57.\u00a0https:\/\/doi.org\/10.1089\/scd.2013.0027<\/a>

Ting-A-Kee R, Vargas-Perez H, Mabey JK, Shin SI, Steffensen SC, van der Kooy D. (2013). Ventral tegmental area GABA neurons and opiate motivation. Psychopharmacology (Berl). 227(4):697-709.\u00a0https:\/\/doi.org\/10.1007\/s00213-013-3002-3<\/a>\u00a0\u200d
Sellings L, Pereira S, Qian C, Dixon-McDougall T, Nowak C, Zhao B, Tyndale RF, van der Kooy D. (2013). Nicotine-motivated behavior in Caenorhabditis elegans requires the nicotinic acetylcholine receptor subunits acr-5 and acr-15. Eur J Neurosci. 37(5):743-56.https:\/\/doi.org\/10.1111\/ejn.12099<\/a>

Ballios BG, Marigo V, van der Kooy D. Directed differentiation of retinal stem cells into photoreceptors and retinal pigment epithelium. In Kaur N, Vemuri M (Eds.), Neural Stem Cell Assays. Wiley-Blackwell, New Jersey, 2013.http:\/\/dx.doi.org\/10.1002\/9781118308295.ch14<\/a>
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Ting-A-Kee R, Vargas-Perez H, Bufalino MR, Bahi A, Dreyer JL, Tyndale RF, van der Kooy D. Infusion of brain-derived neurotrophic factor into the ventral tegmental area switches the substrates mediating ethanol motivation. Euoropean Journal of Neuroscience. 37(6) (2013) 996-1003.https:\/\/doi.org\/10.1111\/ejn.12105<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2012 Publications<\/h2><\/div>

DeVeale B, van der Kooy D, Babak T. (2012). Critical evaluation of imprinted gene expression by RNASeq: a new perspective. PLoS Genetics. 8: e1002600.https:\/\/doi.org\/10.1371\/journal.pgen.1002600<\/a>

Pereira S, van der Kooy D. (2012). Two forms of learning following training to a single odorant in Caenorhabditis elegans AWC neurons. J Neurosci. 32(26):9035-44.\u00a0https:\/\/doi.org\/10.1523\/jneurosci.4221-11.2012<\/a>

Chaddah R, Arntfield M, Runciman S, Clarke L, van der Kooy D. (2012). Clonal neural stem cells from human embryonic stem cell colonies. J Neurosci. 32(23):7771-81.\u00a0https:\/\/doi.org\/10.1523\/jneurosci.3286-11.2012<\/a>

Clarke L, Ballios BG, van der Kooy D. (2012). Generation and clonal isolation of retinal stem cells from human embryonic stem cells. Eur J Neurosci. 36(1):1951-9.\u00a0https:\/\/doi.org\/10.1111\/j.1460-9568.2012.08123.x<\/a>

Grieder TE, George O, Tan H, George SR, Le Foll B, Laviolette SR, van der Kooy D. (2012). Phasic D1 and tonic D2 dopamine receptor signaling double dissociate the motivational effects of acute nicotine and chronic nicotine withdrawal. Proc Natl Acad Sci U S A. 109(8):3101-6.https:\/\/doi.org\/10.1073\/pnas.1114422109<\/a>

Ballios, B., Clarke, L., Shoichet, M., van der Kooy, D. The adult retinal stem cell is a rare pigmented cell in the ciliary epithelium that can differentiate into photoreceptors. Biology Open (2012) 1:237-246.https:\/\/doi.org\/10.1242\/bio.2012027<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2011 Publications<\/h2><\/div>

Pacey LK, Doss L, Cifelli C, van der Kooy D, Heximer SP, Hampson DR. (2011). Genetic deletion ofregulator of G-protein signaling 4 (RGS4) rescues a subset of fragile X related phenotypes in the FMR1knockout mouse. Molecular and Cellular Neurosciences. 46(3): 563-572.https:\/\/doi.org\/10.1016\/j.mcn.2010.12.005<\/a>

Akers KG, Kushner SA, Leslie AT, Clarke L, van der Kooy D, Lerch JP, Frankland PW. (2011). Fetalalcohol exposure leads to abnormal olfactory bulb development and impaired odor discrimination in adultmice. Molecular Brain. 4(29): 1-15.https:\/\/doi.org\/10.1186\/1756-6606-4-29<\/a>

Wu L, Lam S, Cao H, Guan R, Duan R, van der Kooy D, Bremner R, Molday RS, Hu J. (2011).Subretinal gene delivery using helper-dependent adenoviral vectors. Cell & Bioscience. 1(15): 1-7.https:\/\/doi.org\/10.1186\/2045-3701-1-15<\/a>

Clarke L, van der Kooy D. (2011). The adult mouse dentate gyrus contains populations of committed progenitor cells that are distinct from subependymal zone neural stem cells. Stem Cells. 29(9):1448-58.\u00a0https:\/\/doi.org\/10.1002\/stem.692<\/a>

Arntfield ME, van der Kooy D. (2011). \u03b2-Cell evolution: How the pancreas borrowed from the brain: The shared toolbox of genes expressed by neural and pancreatic endocrine cells may reflect their evolutionary relationship. Bioessays. 33(8):582-7.\u00a0https:\/\/doi.org\/10.1002\/bies.201100015<\/a>

Rowland JW, Lee JJ, Salewski RP, Eftekharpour E, van der Kooy D, Fehlings MG. (2011). Generation of neural stem cells from embryonic stem cells using the default mechanism: in vitro and in vivo characterization. Stem Cells Dev. 20(11):1829-45.\u00a0https:\/\/doi.org\/10.1089\/scd.2011.0214<\/a>

Holowacz T, Huelsken J, Dufort D, van der Kooy D. (2011). Neural stem cells are increased after loss of \u03b2-catenin, but neural progenitors undergo cell death. Eur J Neurosci. 33(8):1366-75.https:\/\/doi.org\/10.1111\/j.1460-9568.2011.07632.x<\/a>

Smukler SR, Arntfield ME, Razavi R, Bikopoulos G, Karpowicz P, Seaberg R, Dai F, Lee S, Ahrens R, Fraser PE, Wheeler MB, van der Kooy D. (2011). The adult mouse and human pancreas contain rare multipotent stem cells that express insulin. Cell Stem Cell. 8(3):281-93.\u00a0https:\/\/doi.org\/10.1016\/j.stem.2011.01.015<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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2010 Publications<\/h2><\/div>

Coles BL, van der Kooy D. (2010). Isolation of retinal stem cells from the mouse eye. J Vis Exp. 43: pii:2209.\u00a0http:\/\/dx.doi.org\/10.3791\/2209.<\/a>

Ballios BG, van der Kooy D. (2010). Biology and therapeutic potential of adult retinal stem cells. Can J Ophthalmol. 45(4):342-51.\u00a0https:\/\/doi.org\/10.3129\/i10-070<\/a>

Sturgess JE, Ting-A-Kee RA, Podbielski D, Sellings LH, Chen JF, van der Kooy D. (2010). Adenosine A1 and A2A receptors are not upstream of caffeine's dopamine D2 receptor-dependent aversive effects and dopamine-independent rewarding effects. Eur J Neurosci. 32(1):143-54.https:\/\/doi.org\/10.1111\/j.1460-9568.2010.07247.x<\/a>

Lin CH, Tomioka M, Pereira S, Sellings L, Iino Y, van der Kooy D. (2010). Insulin signaling plays a dual role in Caenorhabditis elegans memory acquisition and memory retrieval. J Neurosci. 30(23):8001-11.\u00a0https:\/\/doi.org\/10.1523\/jneurosci.4636-09.2010<\/a>

Hoffmann MC, Sellings LH, van der Kooy D. (2010). A diacetyl-induced quiescence in young Caenorhabditis elegans. Behav Brain Res. 214(1):12-7.\u00a0https:\/\/doi.org\/10.1016\/j.bbr.2010.05.021<\/a>

Ballios BG, Cooke MJ, van der Kooy D, Shoichet MS. (2010). A hydrogel-based stem cell delivery system to treat retinal degenerative diseases. Biomaterials. 31(9):2555-64.\u00a0https:\/\/doi.org\/10.1016\/j.biomaterials.2009.12.004<\/a>

Grieder TE, Sellings LH, Vargas-Perez H, Ting-A-Kee R, Siu EC, Tyndale RF, van der Kooy D. (2010). Dopaminergic signaling mediates the motivational response underlying the opponent process to chronic but not acute nicotine. Neuropsychopharmacology. 35(4):943-54.\u00a0https:\/\/doi.org\/10.1038\/npp.2009.198<\/a>

Inoue T, Coles BL, Dorval K, Bremner R, Bessho Y, Kageyama R, Hino S, Matsuoka M, Craft CM, McInnes RR, Tremblay F, Prusky GT, van der Kooy D. (2010). Maximizing functional photoreceptor differentiation from adult human retinal stem cells. Stem Cells. 28(3):489-500.\u00a0https:\/\/doi.org\/10.1002\/stem.279<\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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For Earlier Publications: Click Here<\/a><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

know us better Home recent publications 2025 Publications Jacques K, Coles BLK, van der Kooy D. Pancreatic stem cells originate during the pancreatic progenitor developmental stage. Front Cell Dev Biol. 2025 Feb 18;13:1521411. doi: 10.3389\/fcell.2025.1521411. PMID: 40040790; PMCID: PMC11876382. 2024 Publications Maal-Bared, G., \u00a0Yee, M., \u00a0Harding, E. K., \u00a0Ghebreselassie, M., \u00a0Bergamini, M., \u00a0Choy, R., \u00a0Kim, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-445","page","type-page","status-publish","hentry","entry"],"_links":{"self":[{"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/pages\/445","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/comments?post=445"}],"version-history":[{"count":116,"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/pages\/445\/revisions"}],"predecessor-version":[{"id":991,"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/pages\/445\/revisions\/991"}],"wp:attachment":[{"href":"https:\/\/staging-3.com\/university\/wp-json\/wp\/v2\/media?parent=445"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}